Aim: To present a case in which clinical and radiographic signs of healing were obtained after apical plugging of an immature open apex with MTA. Case: A tooth was subjected to radiographic examination revealing an open apex and a periapical radioluscency. The canal was cleaned using intracanal instruments and 5.25% of NaOCl irrigation. To obtain canal disinfection, slurry of calcium hydroxide mixed with sterile saline was temporized in the canal. The patient was asked to return after two weeks for the MTA apical plug placement. The tooth was opened, instrumented and irrigated. Around 4 mm of MTA plug was compacted apically and allowed to set. Thereafter, the remainder of canal system was filled with thermoplasticised gutta- percha. A corono-radicular composite restoration sealed the access. A six-month follow up demonstrated clinically asymptomatic and adequately functional tooth, with radiographic signs of healing.