We report the medical management of a 26-years-old primigravida with a history of recurrent bleeding disorders during childhood. A coagulation profile performed during the 6th month of pregnancy showed a prolonged activated partial thromboplastin time (aPTT) combined with a prolonged 1prothrombin time (PT). An investigation of the coagulation factors by mixing studies showed a deficiency of multiple clotting factors. A working diagnosis of multiple clotting factor deficiency was made. The bleeding risk was considered to be high. She went into spontaneous labor and her labor was carried out in high dependency unit under the care of a senior obstetrician, a hematologist and a hemophilia treatment specialist with therapeutic dose of vitamin k and adequate arrangement of crossed matched blood, FFPs, cryo precipitates, and platelets. A total of 14 FFPs were transfused, 7 during second stage of labor and 7 immediately post delivery. Labor and postpartum period was uncomplicated. She delivered a female baby weighing 2.8kgs.. At D10 postpartum, the patient was discharged uneventfully
