The purpose of this study is to evaluate the diversity of Mollusca in the river Narmada at Jabalpur region (situated in the eastern zone) using diversity and dominance indices. Hence, the samples of Mollusca were obtained from two sites along the river bank, from June 2014 to December 2014. The present study carried out about 9 species of class Gastropoda and 4 species of class Pelecypoda were recorded throughout the study duration. The Shannon’s Index of Mollusca was determined ( = -0.839586). The diversity of all stations was compared with each other. The highest diversity was obtained from site I (Simpson index: 0.173115, : -0.839586) and the lowest diversity was obtained from site II (Simpson index: 0.128353, : -1.024398) that indicate a good variation.