Prevalence And Effect Of Subclinical Hypothyroidism On Pregnancy Outcome-A Study In Eastern India

Research Article
Debasmita Mandal., Sanchita Roy., Rashmi Baid., Amitava Das and Subhankar Choudhary
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Pregnancy, subclinical hypothyroidism, prevalence, neonatal outcome
Abstract: 

Background: Pregnancy with subclinical hypothyroidism may have adverse outcome. Objectives: Our aims are to find out the prevalence of SCH in pregnancy, to analyse the effect of SCH on pregnancy outcome and also to observe recent neonatal outcome. Results: Prevalence of SCH was 4.07. Pregnancies with SCH were more likely to be complicated with pregnancy induced hypertension (26.67%), abruptio placentae (10%), oligohydramnios (16.67%) & IUGR (23.33%). In postpartum period 10% of women with SCH suffered with maternal sepsis & wound dehiscence, whereas subinvolution was seen in 6.67% cases. Neonates also suffered more with RDS (6.67%), neonatal jaundice (20%) and sepsis (13.33%). There was increased incidence of retro placental clots (10.00%) & calcification (13.33%) in women with SCH. Discussion: Subclinical hypothyroidism in pregnancy may result in unfavorable obstetric outcome. Timely screening, therapeutic interventions and multidisciplinary approach will culminate into desired pregnancy outcome.