Occupational respiratory diseases are the major global public health problem that accounts for up to 30% of all work related diseases and 10-20% of deaths are caused by respiratory problems. Occupational exposures are caused by the pathologic response to the working environment of the patient. There is growing unanimity on the deleterious effects of organic dust on respiratory symptoms and functions of industrial workers. Occupational asthma is a disease characterized by variable airflow limitation and/or hyper-responsiveness, and caused by inhalation of toxic or irritating substances in their working place. Asthma and Chronic obstructive pulmonary disease (COPD) are the major respiratory disorder in worldwide. Approximately 235 million people are thought to suffer from asthma globally, and 65million are affected by moderate-to-severe COPD. Most cases of occupational asthma have an allergic mechanism, where there is sensitive to an agent after an extended period of exposure. With respect to cotton dust exposure, chest tightness was the most common respiratory symptom (20.3%). About 14.2% of cotton processing workers were encountering byssinosis. The workers are unwilling to seek medical aid or workplace solutions for their symptoms. And thereby reducing these to improve workers quality of life, and to reduce the social cost of occupational asthma. The increase in morbidity and mortality attributable to occupational exposure has focused attention on the environmental and host factors that cause associated with the clinical entities included under the rubric of this term with a view to early preventive intervention.
