Investigation was carried out during the year 2017 in Maharashtra state with an aim to find out resource use efficiency in pomegranate production. The study utilized the primary data collected from a sample of 80 pomegranate growers spread across 16 villages of two tehsil of each Aurangabad and Jalna districts. These districts were selected purposively because these are well known districts of pomegranate cultivation. Tabular analysis and Cobb-Douglas production function were used for data analysis. Analysis of Cobb-Douglas production for Aurangabad and Jalna districts revealed that sum of regression coefficient found to be 1.44 and 1.33 respectively, indicating increasing return to scale. The selected model explained 41.30 and 32.69 per cent variation in pomegranate production in Aurangabad and Jalna districts, respectively. The result revealed that, expenditure on irrigation charges was 1.360 followed by fertilizers (0.174), plant protection chemicals (0.148) and manures (0.100) were found positive and significant indicating there is scope to increase the use of these resources to increase the output. On the contrary, regression coefficient of labour was (-0.339) negative and non-significant. The ratio MVP/FC found more than unity in case of plant protection chemicals, irrigation, manures and fertilizers. It revealed that use of plant protection chemicals, irrigation, manures and fertilizers needs to increase for optimum level of output. The expenditure on labour need to be curtail.