TORCH infection complex comprises of infections caused by Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), and Herpes simplex virus (types 1 and 2). Syphilis and hepatitis B, Human Immuno-deficiency virus and Zika virus are sometimes included in this group. These infections are associated with adverse fetal outcomes and reproductive failure in pregnant females. Congenital infection by Toxoplasma is particularly severe if the mother acquires the infection during first or second trimester of pregnancy.1-6A trivial viral exanthematous disease in the adults, rubella may have a drastic outcome on the reproductive health and fetal outcome. The infants infected with rubella in utero are born with multiple congenital anomalies like sensory neural deafness, congenital heart disease, microcephaly, mental retardation cataract and blindness, etc. CMV a virus belonging to the herpes viridae family may be the major cause of congenital anomalies in the new born. Genital herpes caused mainly by herpes simplex virus type 2 and 1 during last trimester of pregnancy may be responsible for disseminated neonatal herpes. It is the intrauterine transmission of these infections to the fetus which produces multiple symptoms when the child is born. The diagnosis of these infections is mainly based upon the presence of serum antibodies, particularly IgM in patient’s serum
