Background: Infertility is the most gynecological problem which is increasing all over the world. Many studies were done and many theories were proposed in order to find the correlation between Infertility and hormonal imbalance. Aim: the present study was conducted to study the correlation between some hormones, anthropometric parameters and infertility. Materials and Methods: total 80 women were enrolled for the study among them 40 fertile women were chosen as control while 40 infertile women were serving as study group. The study conducted at obstetrics and gynecology out-patient of Rama medical college and Hospital. The primary investigations of infertility were done to all women. Enrolled subject went for the anthropometric measurements. The hormones were measured with CLIA method by Cobas e411 Results: The mean serum levels of T3, T4 and TSH in infertile women was found to be lower (1.31±0.43, 9.97±2.37 and 6.27±5.93) in compare to fertile women (2.99±9.97, 8.43±3.19 and 5.19±4.99) and there was a statistical significance found between two study group (p <0.5).The mean serum level of FSH and Prolactin were also significantly lower in case group (6.05±1.11 and 12.68±9.46) in compare to healthy subjects (6.85±3.08 and 17.37±5.87)while LH was found to be significantly higher in infertile women. Conclusion: Different hormones such as FSH, LH, Prolactin, TSH, T4, T3, and Anthropometric factors such as BMI and weight play a role in pathogenesis and different mechanisms of infertility.