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An increasing need of nanotechnology in various industries may cause a huge environment dispersion of nanoparticles in coming years. A concern about nanoparticles interaction with flora and fauna is raised due to a growing load of it in the environment. Rapid development and wide applications of nanotechnology brought about a significant increment on the number of engineered nanomaterials inevitably entering our living system. Plants comprise of a very important living component of the terrestrial ecosystem. Studies on the influence of engineered nanomaterials on plant growth indicated that in the excess content, engineered nanomaterials influences plant growth parameters. Therefore, this study revealed that the ZnO nanopartciles and their interactions with plant species affect the anatomical structure of maize and also observed the shrunken morphology of root at higher concentrations of nanoparticles.