The study was conducted on medication adherence and efficacy in Asthma and COPD patients.All patients diagnosed with Asthma and COPD were identified and enrolled in this study as per inclusion and exclusion criteria. Baseline data was collected using peak flow meter, baselinequestionnaire ad data collection fromcounselling and PIL’s was provided to the enrolled patients. At the second visit follow-up was conducted using follow up questionnaire and PEFR values were obtained. Each questionnaire took approximately ten minutes to complete. Measures of symptom distress, general health and well-being, and personal and situational factors including demographic characteristics, social support, self-efficacy, depression, stress, and current adherence to medications were recorded..The results were calculated by using SPSS software version 20 and graph pad prism version 6. Responses to the questionnaires were favourable. Associations among variables were explored paired t test analyses. Beliefs about the importance of adherence and ability to take medications as directed (adherence self-efficacy) were generally positive. The most common reasons for nonadherence to the medications were “simply forgot”, “away from home” and “busy”. The Results from this study provide evidence that structured, co-operative patient education has positive impact in creating awareness about the disease and in improving the medication adherence and efficacy in Asthma/COPD patients.