Metabolic syndrome predisposes the Non Communicable diseases especially cardiovascular disease. The thyroid dysfunctions also induce lipid profile abnormality and enhance the atherosclerotic disease. Thyroid dysfunction is not included in the diagnostic criteria for metabolic syndrome .However when it occurs concomitantly significantly increases cardiovascular risks.
In this study, in the selected patients with metabolic syndrome, the presence of associated thyroid dysfunction among them and the frequency of prevalence of the components were studied and correlated. First 100 patients both men and women attending for NCD checkup in our Government Kanyakumari Medical College Hospitals with Metabolic syndrome as per modified (NCEP – ATP III criteria) in the last one year is included in the study. As a cross section control study equal number of matched patient without metabolic syndrome attending the casualty are included as control After obtaining approval of Ethics Committee of the institution, for all these patients Fasting blood sugar, Lipid profile, and Thyroid function test were (TSH and FT3) carried out along with measurement of Body mass index (BM), blood pressure and waist circumference. .
In the 100 metabolic syndrome patient included in this study overall 42% had subclinical hypothyroidism and 26% overt hypothyroidism rest 32% were Euthyroid. However in women 55% of them had subclinical hypothyroidism and 23% overt thyroid, 22% were Euthyroid.
Central obesity is high in post menopausal women and also HDL cholesterol.
Our study concludes, majority of patients with metabolic syndrome have thyroid dysfunction and more so females have more thyroid dysfunction. Patients with obesity and diabetes mellitus had more evidence of Hypothyroidism. Metabolic syndrome with thyroid dysfunction precipitates the atherosclerotic heart diseases. It is recommended to include thyroid function estimate as a mandatory study in people with metabolic syndrome.
