Purpose: The purpose of our study was to perform a combined analysis of retrospective and prospective study of antiplatelet drugs and statin to evaluate the safety and efficacy of the antiplatelet drugs and statin prescribed in our study. To Understand the mechanism of antiplatelet drugs and statin, to evaluate the use of antiplatelet agents and statin, to find the best antiplatelet drug and statin according to the clinical indications and to formulate future treatment guidelines and protocol. Method: 150 cases were collected and the data collection form will be prepared and used. This form mainly contains the demographic details of the patients and medication chart. All information relevant to the study was collected from outpatient as well as inpatient department from the time of admission till the date of discharge after taking consent from patient. Result: This is a combination analysis of prospective and retrospective studies for therapeutic management of coronary artery disease 150 cases were collected considering the exclusion and inclusion criteria. The results interpreted from observational study was found to be significant based on Age, gender, commorbidities, Dual anti-platelet therapy prescribed, combination therapies given in both in-patients and out-patients. Statistical analysis showed that, there was a significant improvement in coronary artery disease and decrease in clinical presentations after therapeutic management using antiplatelets and statins
