Ultrasonic investigation finds extensive applications in probing in to the physico-chemical behavior of liquids leading to an understanding of the liquid state. This technique has been adequately employed to study the properties of any substance to understand the nature of molecular interactions in pure liquids and ionic interactions in protein salt solutions. The measurements of ultrasonic velocity of liquid play an important role in understanding the nature of molecular systems. The present work deals with the molecular interaction studies on some amino acids in non-aqueous solutions at various temperatures. From the measured parameters such as velocity, density, viscosity and some derived parameters like internal pressure, free volume, Rao’s constant and Wada’s constant are calculated. The study reveals the structural changes occurring in the solution through the FTIR study of L-Arginine derivatives in polar solvent. The diagnostic bonds observed at certain frequencies are assigned to the carbonyl stretch present is identified. The assignment of FTIR spectra has thrown light on the interaction between the solute and the solvent.
