Toxic Effect Of Arsenic Trioxide On Biochemical Response In Catfish, Clarias Batrachus

Arsenic is a widespread ubiquitous toxicant in the world and its toxicity in chemical form, with inorganic forms being referred more toxic than the organic form. The impact of toxicity of arsenic trioxide on certain biochemical parameters of the catfish, Clarias batrachus has been analysed following exposure of lethal concentration (LC50 value- 84 mg/l) of arsenic trioxide for 24, 48, 72 and 96 hours. To estimated serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) were observed in both control and arsenic trioxide exposed catfish. The level of SGOT and SGPT were significantly increased to control value during the treatment of arsenic trioxide.