The professional knowledge and skills possessed by most teachers for translating the evaluation guide of Nigeria’s 9-year Basic Education Curriculum (BEC) into action in the classroom is in doubt. This work set out to ascertain teachers’ knowledge and skills to frame suitable questions using the Basic Science curriculum evaluation guide. The study shows that Basic Science teachers have adequate knowledge and skills to frame suitable questions, or give instructions that will help students in 33(53.23%) of the items of Basic Science teacher guide for students’ evaluation; inadequate knowledge and skills to frame suitable questions, or give instructions that will help students provide answers relating to items in 29 (46.77%) of the items of Basic Science teacher guide for students’ evaluation. Necessary skills and knowledge that are required of teachers for proper translation of the evaluation guide of Nigeria’s 9-year BEC into action in the classroom are examined.