Pleomorphic adenoma (PA) is the most common benign mixed salivary gland neoplasm that accounts for 60% of all benign salivary gland tumors. It has a remarkable degree of morphological diversity. PA of minor salivary gland in the palate is a common entity. We report the case of a 40- year-old female who presented with a painless, slow growing swelling of the palate over the last 1 year. Computed tomography (CT) scan revealed an isodense structure in the palate causing bony erosion of the palatal region and perforating into the nasal cavity. Incisional biopsy report revealed PA of the palate. The entire tumor mass was excised along with the overlying mucosa followed by removal of the perforated bony structure. The Greater palatine vessels and nerve were dissected from the tumor mass and ligated. It was followed by chemical cauterization using carnoy’s solution on the exposed bone to kill any remnants of tumor cell. The excised tumor along with excised palatal bone was sent for histopathology. A preformed stent encasing collagen and perio-pack was used to cover the defect. Histopathological examination confirmed the diagnosis of cellular PA of minor salivary gland. Patient has been on regular follow ups with no signs of recurrence and satisfactory healing
