Uric acid levels in early pregnancy as a predictor of preeclampsia And gestational diabetes mellitus

Research Article
Baliga Pundalik and Thunga Suchitra
DOI: 
xxx-xxxx-xxxx
Subject: 
Mediclne
KeyWords: 
GDM, GCT, OGTT, Preeclampsia
Abstract: 

A Prospective study was conducted in a tertiary hospital to examine whether uric acid levels in early pregnancy were associated with development of GDM (Gestational Diabetes Mellitus)and Hypertensive disorders during the second half of pregnancy in178 women. Women who came before 20 weeks of pregnancy for antenatal check-ups underwent uric acid level estimation, followed by GCT (Glucose challenge test) and OGTT ( Oral glucose tolerance test)if required between 24-28 weeks periods of gestation (for GDM). These women were followed up until delivery for development of Hypertensive disorders complicating pregnancy. Results showed the prevalence of Preeclampsia and GDM was 0.57% and 2.28% respectively. In the present study, Uric acid as a predictor for both Preeclampsia and GDM was found to be statistically insignificant. Our findings did not support the hypothesis that assessing uric acid concentration in pregnant women in the first trimester predicts the development of GDM and Preeclampsia.