Aims
Due to the increase of multiresistant microorganisms causing urinary tract infection (UTI), this study aimed to identify the frequency of uropathogens in 2000 patients with clinical suspicion and profile of antimicrobial susceptibility of Escherichia coli facing the positive urine cultures.
Methods
The samples were processed in a clinical laboratory convened exclusively by the Unified Health System, and the Microbiological Research Lab - Uniararas in the period between April and July 2012.
Results
The UTI was present in 247 (12.35 %) patients. The frequency of major uropathogens were Escherichiacoli 75.71%; Klebsiella pneumoniae 8.50%; Burkholderiacepacia3.24%; Enterobacter sp 2.83%; Proteus mirabilis 2.43%; Pseudomonas aeruginosa 2.43%; Staphylococcus aureus2.03%; Streptococcusagalactiae 1.22%; 1.21% Staphylococcus saprophyticus and Streptococcus sp 0.40%. It was observedthat the E. coli was the most frequent uropathogen, with significant difference (p <0.05).Among outpatient samples, 2.14% of E. coli producing strains showed beta-lactamase and 0.53% resistantto imipenem, which proved the most effective antibiotic against E. coli followed by the amikacin with resistance 2.14%. Moreover, E. coli was resistant to cephalothin in 88.70% of the tests, while beingresistant to nalidixic acid of 48.67%.
Conclusion
The results reported here demonstrate that the etiology of urinary tract infections is similar to that found in other parts of the world, and the highest frequency was E. coli. The resistance pattern of this uropathogen may have different characteristics according to the historical consumption of antimicrobials in each community. Thus, it is important that epidemiological data on the frequency of infectious agents along with the profile of antimicrobial susceptibility are announced periodically with the intention of helping the medical and clinical information for new therapeutic options.
