Background: Traditionally, root of Aerva lanata are used as sap for eye-complaints, an infusion is given to cure diarrhoea, kidney stone and in snake bite treatment. Aim: The aim of this study was to evaluate in-vitro anti-bacterial activities of solvent extract of the root of Aerva lanta. Methods: Aerva lanata Plant was screened using the agar well diffusion and broth micro-dilution assay. The purity of isolated phytosterol was checked by TLC, column and qualitative phytochemical analysis and total phytosterolwere quantified. Results: In the current study, the inhibitory action of the phytosterol was found to increase with an increase in concentration against all bacterial strains. The maximum zone of inhibition was observed at the concentration of 500 µg/ml against all the bacteria. In this study, the S. aureus and E. coli are the more susceptible than the other selected human pathogenic bacteria. Conclusion: This study shows that Aerva lanata, could be a valuable source for antimicrobial properties and helps to produce antimicrobial agents to treat human pathogenic infections.
