Objective: In the present study the methanolic extract of stem of Alpinia purpurata was studied for alpha amylase and alpha glucosidase inhibition using an in vitro model. Methods: The methanolic extract was also examined for its antioxidant activities by using free radical 1,1-diphenyl-2-picryl hydrazyl (DPPH) scavenging method. Results: The study revealed that the different concentration of extracts exhibit potent radical scavenging activity using DPPH as substrate. The stem of Alpinia purpurata exhibited significant α-amylase (70%) and α-glucosidase (87.8%) inhibitory activities at the concentration 100 µg/ml respectively and well compared with standard acarbose drug. Conclusion: Therefore, it is suggested that the methanolic extract of stem of Alpinia purpurata is a potential source for natural antidiabetic and antioxidant compounds and could have potential use in the management of diabetes mellitus.
