The depletion of fossil fuels and need for sustainable development requires that fermentation Itaconic acid production replaces petroleum-based methods of Itaconic acid production. Itaconic acid is small organic acid with one or more carboxylic acid groups. Itaconic acid copolymers are used in packaging, substitutes for conventional plastics materials. Itaconic acid is also used for special lens and cut stone. Extraction of organic acids has been studied using tri-n-butyl phosphate. In this equilibrium study, a mixture of inert (1-Dodecanol, 1-Butanol & 1-Octanol) diluents is used to provide the appropriate physical properties of extractant (TBP) and improved extraction efficiency. Reactive Extraction with specific extractant and a proper combination of extractant and diluents provide the higher capacity and selectivity for Itaconic acid. The result of equilibrium experimental study is useful in extraction processes for recovery of Itaconic acids from fermentation broths.
