Association Of Plasma Glucose Levels With Estimated Average Glucose Levels In Diabetic Patients

Research Article
Dipsha Kriplani, Akshay Kriplani and Arvind Bhake
DOI: 
xxx-xxxx-xxxx
Subject: 
Science
KeyWords: 
fasting plasma glucose, glycosylated hemoglobin, estimated average glucose levels, diabetes.
Abstract: 

Background: The aim of the study was to measure the fasting plasma glucose levels and the glycosylated hemoglobin levels of type 2 diabetic patients and to calculate the estimated average glucose (eAG) levels to establish a correlation between the fasting glucose levels and the estimated average glucose levels. Methods: Fasting blood glucose (FPG) levels was measured by glucose oxidase - peroxidase method and glycosylated hemoglobin level was measured by Latex agglutination inhibition assay. Estimated average glucose (eAG) levels expressed in mg/dl were calculated by Nathan’s regression equation: eAG= 28.7 x HbA1c - 46.7. Pearson correlation coefficient (r) was used to establish a correlation between FPG & eAG and a value of r=0.92 was considered strong enough to establish a correlation between HbA1c and estimated average glucose (eAG). Result: Pearson’s correlation coefficient was found to be strong enough  to justify a correlation between the values of HbA1c and estimated average glucose (eAG). Conclusion:  Since estimated average glucose values correlate with the values of glycosylated hemoglobin and are reported in terms of mg/dl, reporting it along with HbA1c assists the clinicians to have a better understanding of the status of glycemic control of the patient