Thickness, volume, histological compositions are the significant features influencing the success of connective tissue grafts (CTG). Laser assisted de-epithelialized gingival graft (DGG-L) is a novel graft harvesting technique quoted in literature, proposed to procure adequate collagen-rich connective tissue from lamina propria of the palatal mucosa. This case series aimed to compare the clinical outcomes following use of de-epithelialized gingival grafts DGG-L / conventionally harvested CTG along with coronally advanced flap (CAF) in management of gingival recession defects. 10 Miller’s Class I / II gingival recession sites were randomly treated either with CAF+DGG-L or CAF+CTG. Results were expressed in terms of the mean root coverage%. At the end of 6 months, both the treatments resulted in 100% root coverage. Histological examination of grafts demonstrated that DGG-L composed of larger amounts of fibrous connective tissue and lower amount of fatty glandular layer compared to conventional CTG.
