Development Of Dengue Database By Using Bioinformatics Tools And Techniques

Research Article
Vanitha NM., Jayarama Reddy and Ranganathan T.V
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Dengue, Polyprotein, Database, Bioinformatics and Genomics.
Abstract: 

Dengue database is an effort to collect information about the dengue virus, dengue virus genes, dengue virus drugs targets and drugs, disease into a central portal to facilitate dengue researchers from several disciplines such as drug discovery, vaccine development, epidemiology and comparative genomics. The database also serves as link to Global Sequence Information eg. NCBI, DDBJ, EMBL, PDB, Expasy, Medical Literature like PubMed etc. The main aim of this project is to create a web enabled database for the Dengue Disease drugs targets and provide most useful information Like Genomic study, gene Information, Drug target information for the researcher. The Dengue genome encodes a single large open reading frame that is translated to form a viral polyprotein. The dengue polyprotein is cleaved by viral and host proteases to produce 3 structural proteins and 7 non-structural (NS) proteins. We have modeled all structural and nonstructural proteins by using bioinformatics tools and techniques and presented in this