Dosimetric Comparison Of 3d Conformal Radiotherapy (3d-Crt) And Volumetric Modulated Arc Therapy (Vmat®) In Cervix Cancer: Experience Of Mohammed Vi Center For Cancers Treatment Casablanca

Research Article
Saad Zouiri, Ilham Khalfaoui, Mounir El Hassani, Abdellatif Ennakri, Abdenebi Elmoutaoukkil, Sellama Nadifi, Fadwa Qachach, Zineb Bouchbika, Nadia Benchakroun, Hassan Jouhadi, Nezha Tawfiq, Souha Sahraoui and Abdellatif Benider
DOI: 
http://dx.doi.org/10.24327/ijrsr.2019.1006.3533
Subject: 
science
KeyWords: 
Cervix cancer, Conformal radiotherapy, volumetric modulated arc radiotherapy.
Abstract: 

Backgraound: Radiochemotherapy supplemented with brachytherapy is a standard in the treatment of locally advanced cervix cancer. Conformal radiotherapy (3D-CRT) does not allow a good organ at risks sparing. Technological developments led to the emergence of Modulated Volumetric Arc Therapy (VMAT®), which showed a dosimetric value in pelvic irradiation compared to conformal radiotherapy (3D-CRT) for intestinal sparing and homogeneity of planning target volume coverage while decreasing treatment time. The objective of the study is the dosimetric comparison of the conformal radiotherapy technique and VMAT® in cases of cervix cancer. Methods: This is a comparative retrospective study of 17 cases treated in our center for cervix cancer by pelvic radiotherapy without lumbar-aortic radiation. The cases that received a 3D-CRT treatment were simulated in VMAT® and those who received a VMAT® irradiation were simulated in 3D-CRT. Data entry was done on Excel software and static analysis by Statistical Package for the Social Sciences (SPSS) software version 21.0. Results: The mean coverage of the Planning target volume was lower with VMAT® (p <0.001). This technique allowed better intestinal sparing (p <0.001) , better bladder (p <0.001) and rectal sparing (p <0.001). Monitor units (MU) in VMAT® are much more important than in conformal radiotherapy (3D-CRT) (p <0.001) which influences the treatment time; 4 minutes for VMAT® and 3 minutes for 3D-CRT. Conclusion: The VMAT® is more interesting in matters of organ at risks sparing compared to the 3D-RCT, but with more monitor unites (UM ) and a relatively longer processing time.