Immunizations are an important part of health promotion and disease prevention strategy for all children. It is the most common source of iatrogenic pain in childhood. The pain associated with such injections is a source of distress for children. This study aims to assess the effectiveness of ice application on pain among toddlers receiving immunization in selected immunization clinics. A quasi experimental post-test only design was adopted. Convenience sampling technique was used to select the toddlers. Data was collected using FLACC behavioral pain assessment scale. Based on the objectives and hypotheses, the obtained data were analyzed using descriptive and inferential statistics. The result of the study showed that the mean post-test value computed between experimental and control group pain scores are statistically significant. The present study concludes that ice application is a safe and effective complimentary alternative method in pain management, and it can be safely added to many other tools used by pediatric nurses and physicians
