Gastroesophageal reflux disease is a disease experienced by adults at least once a week. The history of the patient and their response of empirical trial with the proton pump inhibitors, H2 receptor antagonist and other antacids which are used to treat the Gastroesophageal Reflux Disease. Diagnosis of the disease can be done based on the severity of Gastroesophageal Reflux disease in primay care. The limited diagnostic information of the endoscopy provides that the majority of the patients will not have visible lesion on Gastroesophageal reflux disease. This Gastroesophageal reflux disease is caused by the passage of the gastric contents from the stomach into the esophagus and causes the symptoms and damages the mucosa. Obesity and smoking are the other genetic factors with which GERD occurs which might be important. The negative association of helicobacter pylori exists, but the eradication does not cause reflux disease. Gastroesophageal Reflux disease is a tipically chronic disease which is associated with the development of complications and increasing severity and significance of the disease.
