Screening measures help to maximize the safety of blood transfusion. Though there are scientific and technical sophistication in the safety of blood donation, mainly hepatitis B virus (HBV) still remain the most transmitted infectious pathogenic agents. The blood bank testing accuracy cross checked by retesting of donors samples collected during blood donation camp, Raigadh. Total 382 samples were retested by ELISA at National Institutr of Immunohaematology, ICMR, Mumbai. There was False Positive 5 (1.30%) and False Negative 5 (1.30%). The anti-HBc ELISA also done for same samples which was 12.82% positive. False negative percentage directly indicates the residual transfusion of HBV 1.30%, whereas the false positive rate (1.83%) indicates the pointless wastage of blood units. External Quality Assurance Program has to be implemented mandatorily to overcome the problem of false reporting, along with intense training of blood bank personals.
