Hyperprolactinemia is usually regarded as the persistent increase of prolactin to the amounts exceeding normal values. Prolactin is a globular protein synthetized and secreted by lactotrophs in anterior pituitary gland. When prolactin levels exceed normal levels, it can cause major problems. Several conditions may cause hyperprolactinemia. Physiological factors such as pregnancy, lactation, sexual intercourse, sleep, exercise, and stress might influence on prolactin level; however, the most prevalent cause of hyperprolactinemia is medicines. The present study was formulated in order to determine the effect of hyperprolactinemia on reproduction, cancer, behavior, and obesity. Also, a short part was dedicated to treatment of hyperprolactinemia.
