Malaria and typhoid are major aethiological considerations in both acute and prolonged fever of unknown origin in the tropics. The present study investigated the incidence of malaria and typhoid in acute fever and their commonest cause. A total of 108 blood samples collected from patients presenting febrile condition suggestive of malaria and typhoid fever and analyzed using standard microbiological techniques. The result revealed that typhoid (32.40%) is more prevalent than malaria (10.80%) in acute fever. Antigen detection kit method (72.72%) is more sensitive than peripheral blood smear (27.27%) for detection of malaria. In conclusion, typhoid fever is more common in acute fever due to poor hygiene practice .HRP2- based RDT has shown superior sensitivity compared to microscopy in diagnosis of malaria and may be more suitable for screening of malaria infection.
