Introduction: The chemotherapy aims to destroy malignant cells, though it also acts on normal cells. It may cause unpleasant local effects and they may spread to other organs. Among the effects are the oral cavity changes such as: xerostomy, mucosities, traumatic or fungal lesions as well as taste disorders that cause discomfort to the patient with the functional, esthetic and phonetic commitment that make social reactions worse. Objective: Verifying the oral manifestation arise from chemotherapy in patients suffering from head, neck, breast, prostate, colorectal and stomach cancer. Methodology: It is about a cross-sectional study made with 43 patients diagnosed with cancer and submitted to chemotherapy, treated at NossaSenhora da Conceição Hospital. The patients were separated into five groups according to the type of cancer. The data collection were accomplished through a questionnaire and oral cavity tests. The results were imported to Excel spreadsheets and then exported to SSP* version 15 to a descriptive analyses and simple frequency distribution. Results: The results showed that 25 (58,1%) were male and 18(41.9%) were female. The patients’ range was 60 to 69 years old. The main symptoms found were xerostomy 22 (51,2) and dysgeusia 19 (44,2%). Conclusion: They show to have the knowledge about the effects of oral manifestation arising from chemotherapy, having xerostomy and dysgeusia are the most oral simptoms found.
