Starvation, characterized by a severe lack of essential nutrients, has far-reaching consequences on physical and mental health. This article reviews the pathophysiology and clinical management of starvation from both Modern Medical Science and Ayurvedic perspectives. Modern treatments focus on refeeding and addressing metabolic imbalances, while Ayurveda offers holistic solutions through dietary adjustments, herbal remedies, and lifestyle practices. This review emphasizes the benefits of integrating modern and Ayurvedic approaches for comprehensive management and recovery and highlights the potential of integrating modern medical and Ayurvedic management strategies for treating starvation, advocating for a patient-centred approach that leverages the strengths of both medical systems