Association of Helicobacter pylori in Oral Squamous Cell Carcinoma – A Retrospective Study Using Polymerase Chain Reaction
Background: Oral Squamous Cell Carcinoma (OSCC) is the predominant malignancy of the oral cavity, frequently associated with habits such as tobacco and alcohol usage. Helicobacter pylori (H. pylori), a known gastric pathogen, has been hypothesized to play a role in OSCC pathogenesis. Aim: To evaluate the association of H. pylori in OSCC using Real-time Polymerase Chain Reaction (RT-PCR) on formalin-fixed paraffin-embedded (FFPE) tissue sections.