Past Issue

Background: Insomnia is a widespread sleep disorder where individuals experience difficulty in initiating sleep, maintaining it, or achieving restful sleep, even when the environment is conducive. This condition can significantly disrupt personal, social, and occupational well-being. It may present as short-term, temporary, or chronic, and is frequently associated with other health issues such as anxiety, depression, cardiovascular disorders, and persistent pain.

Introduction:  Staphylococcus aureus is the most common virulent pathogen and MRSA is a major cause of Hospital and Community acquired infections.Macrolide-Lincosamide-StreptograminB (MLSB) group of antibiotics especially Clindamycin is the next preferred agent to treat MRSA infections due to emergence of vancomycin resistant strains, however resistance to these antibiotics is of major concern. The Objective of the study is to Detect and Characterize MLSB   resistance phenotypes among MRSA isolates.

The present study aims to explore the utilization of Information and Communication Technology (ICT) in secondary schools within Prakasam district. A comprehensive review of both Indian and international literature was undertaken to provide a strong theoretical foundation. The study adopted a descriptive survey method to gather relevant data. A total of 100 students from various secondary schools in Prakasam district constituted the sample. To ensure representativeness, the stratified random sampling technique was employed.

The search for new antimicrobial agents has accelerated due to the rise in antibiotic-resistant bacterial infections, and green-synthesized silver nanoparticles (AgNPs) have emerged as a viable substitute. The stem extract of Rotheca serrata (L.) Steane & Mabb., a medicinal plant recognized for its bioactive phytoconstituents, was used in this study to create silver nanoparticles. AgNP production was verified by UV-Vis spectroscopy, which revealed a distinctive surface plasmon resonance peak at about 400 nm.

Vermicomposting is an eco-friendly solution to the worldwide impacting problem of solid waste management. The present study involves the assessment of use of vegetable waste and corrugated cardboard waste as raw material and their evaluation in the growth of Catharanthus roseus and Tagetes erecta plants. Several variables including moisture content, pH, dry weight, calcium, magnesium and phosphates were assessed at regular intervals to get information about the nutrient qualities. The results showed an increases in the moisture content over the time due to active performance of earthworms.

Sydnones are very important members of the class mesoionic compounds. A series of schiff base derivatives has been synthesized by condensing 4-(((4-aminophenyl) amino) methyl)-3-(3-nitrophenyl)sydnone with KCNS and Br2 in presence of glacial HAc- followed by the reaction with substituted aromatic aldehydes. The synthesized compounds were characterised and evaluated for antimicrobial activities. The newly synthesized compounds were screened against representatives of Gram-positive and Gram-negative bacteria and fungi.

Anidra, referred to as Insomnia in contemporary medicine, is recognized in Ayurveda as a consequence of doshic imbalances, primarily involving Vata, with secondary disturbances in Pitta and Kapha. These doshas, considered Tristhuna (the three pillars of health), are vital for maintaining physiological harmony. Anidra is classified under Vataja Nanatmaja Vyadhis and emphasizes the essentiality of Nidra (sleep) as one of the three Upasthambhas (pillars of life), along with Aahara (nutrition) and Brahmacharya (celibacy or self-discipline).

This research examines the historical as well as contemporary landscape of family owned businesses in India and around the world. It focuses on a select group of prominent family businesses to analyse their longevity, impact, and value contribution. The paper highlights adaptability and long-term vision for longevity of family businesses in India. This study aims to offer a deeper understanding of the role of these family businesses in India’s economic development.

Objective:To evaluate the practical value of Infrared forehead thermometer (IFT)s in body temperature screening and provide evidence-based recommendations for optimizing measurement site selection in febrile patients. Methods: For the pre examination triage patients, the forehead temperature gun was used to select the forehead (forehead method), wrist (wrist method) and neck (neck method) for temperature measurement, and the mercury thermometer was used to measure the axillary temperature (standard method).

Drug delivery systems (DDS) are a crucial area in pharmacology, ensuring proper delivery of therapeutic agents with enhanced efficacy and decreased side effects. Conventional drug delivery approach, which includes oral, parenteral, transdermal, and topical systems, has been widely employed but often suffers limitations such as poor bioavailability, non-specific targeting of drugs, and frequent dosing needs.